Tips for designing and implementing folder permissions on a AD environment

Anyone has come across any white papers or any blogs that provide tips on designing and implementing folder permissions correctly on a windows environment. Our folder structure is a mess and I've been tasked to fix it.
Comments
[h=1]File and Folder Permissions: https://msdn.microsoft.com/en-us/library/bb727008.aspx[/h]TIP: design patterns - Structuring Access Control In Hierarchical Object Graph - Programmers Stack Exchange
Permissions for files and folders: Establishing File & Folder Level Permissions, Network Drives
Hope this helps!
“The measure of an individual can be difficult to discern by actions alone.” – Thane Krios
IT
--Network
----Manuals
----Configs
----Firewalls
--Servers
----etc
--Help Desk
----etc
--Information Security
----etc
--Programmer
----etc
--Etc